【Physicochanemical Cov Khoom Siv】
Prazathantel yog ib qho ooquinoline pyrazine deradative, tshwm sim raws li lub dawb lossis tawm {{mrystalline hmoov. Nws muaj qhov iab iab, yog insoluble hauv dej thiab ether, soluble hauv ethanol, thiab yooj yim soluble hauv chloroform.
【Kev ua thiab siv】
Prazathantantel yog qhov tshiab zoo tshaj plaws tshiab -}} spectrum anthelmintic zoo tiv thaiv cestodes thiab trematodes. Nws cov tshuab kev ua tau tsis tau ua tiav tag nrho tab sis tuaj yeem cuam tshuam cov calcium ntawm calcium thiab sodium rau cov cab, ua rau cov tuag tes tuag taw. Nws ua kom pom qhov tseem ceeb tiv thaiv ob qho loj thiab cov laus theem ntawm cov cestodes feem ntau thiab tuaj yeem ua rau schistosomes hauv lub siab mus rau daim siab mus rau daim siab, uas lawv tuag.
Lub spectrum ntawm kev ua haujlwm feem ntau suav nrog:
Yaj: Moniezia Spp.
Nyuj, yaj, thiab npua: Cysticercus tenuicollis.
Nyuj thiab yaj: Schistosoma japonicum.
Dev, miv, thiab nqaij qaib: Ntau tus cestodes.
【Pharmacokinetics】
Prazatantel tau nrawm thiab nqus tau tom qab cov tswj tau tom qab lub cev thiab faib tawm thoob plaws lub cev, nrog cov siab tshaj plaws hauv daim siab thiab lub raum. Lub sijhawm tshem tawm ib nrab - lub neej sib txawv ntawm hom:Npua (1.1h)
Kev sib cuam tshuam yeeb tshuaj:
Concurrent siv nrog albendazole lossis dexamsasone yuav txo cov ntshav ntshav siab ntawm cov ntsiab lus, muaj peev xwm ploj zuj zus nws txoj kev ua tau zoo.
Cov nyom tshwm sim】
Prazatquantel ua yeeb yam tsawg kawg ntawm kev lom zem hauv cov tsiaj, tshwj xeeb ntawm cov tshuaj pleev qhov rooj. Tsawg dua 5% ntawm cov dev yuav muaj kev cuam tshuam pa hluav taws xob xws li anorexia, ntuav, lossis zawv plab.
Thaum muab tshuaj ntawm kev txhaj tshuaj, cov nyom ntawm cov dev thiab miv yuav nce ntxiv, suav nrog:
Cov dev: Qhov mob ntawm qhov chaw txhaj tshuaj, tsaug zog, thiab tsis khov.
Miv: Anorexia, ntuav, raws plab, thiab kev ntxhov siab.
Ntawm cov koob tshuaj ntau, nyuj yuav ua rau nce lub cev kub, bloat, thiab cov leeg tshee.
【Tshuaj thiab Administrial】
Thawj coj:
Rau cestodiasis:
Nyuj & Yaj: 10-20 mg / kg lub cev hnyav, muab ob zaug nrog ib 3-4 hnub sib nrug.
Npua: 10-35 mg / kg lub cev hnyav, muab ob zaug nrog ib 3-4 hnub sib nrug.
Cov dev & miv: 2.5-5 MG / KG lub cev hnyav, muab ob zaug nrog ib 3-4 hnub sib nrug.
Nqaij qaib: 10-20 MG / KG lub cev hnyav, muab ob zaug nrog ib 3-4 hnub sib nrug.
Ntses: 48 mg / kg lub cev hnyav, muab ob zaug nrog ib 3-4 hnub sib nrug.
Rau schistosomiasis:
Nyuj & Yaj: 10-35 mg / kg lub cev hnyav, ib koob.
Cim npe nrov: prazatquarantel, cov chaw tsim khoom, cov chaw muag khoom, chaw tsim khoom, lag luam wholesale, kev cai
