Helbuty90 (Coated Sodium Butyrate 90%)
Sodium butyrate
[Physicochemical cov khoom thiab cov metabolism ntawm sodium butyrate]:
Sodium Butyrate muaj cov molecular qauv cha₃ch₂chchiCoonsa. Nws yog cov hmoov dawb, hygroscopic nrog lub ntsiab lus melting ntawm 250.0-253.0 Degree thiab qhov txawv Rancid cheese- zoo li tsw. Raws li cov ntsev hauv organic ntawm butyric acid, nws yog soluble heev hauv dej thiab ruaj khov nyob rau hauv lub teeb thiab kub. Butyric acid yog luv-}}}}}}}, bifabbacterium) los ntawm fermentation carbohydrates thiab protein nyob rau hauv cov hnyuv. Butyrate tuaj yeem nkag mus rau daim siab ntawm lub portal leeg portal thiab hloov dua siab tshiab rau hauv Ketone lub cev, fatty acids, thiab cov roj cholesterol. Lub cev Ketone lub cev muaj peev xwm ua tau zoo sib xws rau hauv adenosine triphosphate (ATP), muab lub zog rau lub plab hnyuv. Cov seem unabsorbed nkag mus rau lwm cov plab hnyuv siab raum thiab cov ntaub so ntswg rau cov metabolism.
[Kev siv hluav taws xob ntawm sodium butyrate nyob rau hauv kev tswj hwm plab hnyuv noj qab haus huv thiab nqaij qaib]:
(1) Sodium Butyrate tswj cov qauv txheej txheem ntawm cov hnyuv mucosa, nce cov pob zeb loj {-}} crypt qhov tob sib piv.
(2) Nws ua haujlwm ua lub zog ceev ceev rau cov hnyuv txhad epithelial.
(3) Nws txhawb txoj hnyuv loj hlob hauv cov tsiaj txhu thiab nqaij qaib, txhim kho cov kev sib txheeb ntev ntawm cov zaub mov hauv lub plab zom mov, thiab ua kom muaj plab hnyuv tawv nqaij.
(4) sodium butyrate stimulates lub zais ntawm immunoglins thiab lwm yam kev tiv thaiv kab mob hauv plab hnyuv ua haujlwm, txhim kho cov teeb meem hauv plab hnyuv ua haujlwm thiab txo qhov tshwm sim ntawm kev o.
(5) Nws txhawb nqa kev ua si ntawm cov hnyuv enzymes hauv txoj hnyuv.
(6) Nws txo qis plab phy thiab txhim kho lub plab zom mov microecology.
[Lub tswv yim]:
Ntsiab lus 1: Luv - saw pain fatty acids (scfas) yog cov organic fatty acids nrog roj carbon xij ntawm 1-6, feem ntau yog acetate, propionate, thiab butyrate. Qeb ntawm Butyrate yog qhov taw qhia tseem ceeb ntawm txoj hnyuv noj qab haus huv.
Ntsiab lus 2: Undigested carbohydrates thiab fibrous polysaccharides uas mus txog rau txoj hnyuv loj yog hloov mus rau hauv cov kab mob ntawm cov kab mob anaerobic. Txhua qhov kev cuam tshuam rau cov substrates (undigested carbohydrates thiab fibrous polysaccharides) lossis cov kev ua ntawm cov kab mob anaerobic yuav ncaj qha rau scfa ntau lawm.
Ntsiab lus 3: SCFAS, Tshwj xeeb Butyrate, yog qhov tseem ceeb ntawm cov as-ham rau lub colonic mucosa. Butyrate oxidation account rau 75% ntawm cov pa oxygen hauv colonic epithelial hlwb.
[Nquag khoom xyaw]: Sodium butyrate
[Cov ntsiab lus]: Ntau dua los yog sib npaug rau 90%
[Molecular formula]: Ch₃chchchch₂coonsa
[Molecular hnyav]: 110.09
Zoo tshav ntuj tau mob siab rau kev tshawb fawb thiab kev tsim cov sodium butyrate khoom rau ntau xyoo caum. Lub tuam txhab tau tsim cov khoom siv coated xws li welbuty30 (coated sodium butyrate 30%) thiab ua rau muaj peev xwm ntau lawm ntawm 99% butyrate hmoov. Zoo tshav ntuj pab pawg cov tsiaj txhu tau muag rau ze li 100 lub teb chaws thiab cheeb tsam hauv ntiaj teb.
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