4-(5-Methyl-3-Phenyl-4-Isoxazolyl) benzenesulfonamide
CAS Nr.: 181695-72-7
[Synonyms]
4-(5-methyl-3-phenyl-1, 2-oxazol-4-yl)benzenesulfonamide
4-(5-Methyl-3-phenyl-4-isoxazolyl) benzenesulfonamide
4-(5-Methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
benzenesulfonamide, 4-(5-methyl-3-phenyl-4-} isoxazolyl)-
CBN No.: CB4754453
Molecular Formula: C16H14N2O3S
Molecular Luj: 314.36
MDL No.: MFCD00950568
MOL File:181695-72-7.mol
Melting point 162-164 degree
Boiling point 481.2 ± 55.
Qhov ceev 1.303 ± 0.06 g/cm3(Xav tau)
cia temp. chav kub
solubility DMSO: >25 mg/ml
pka 9.83 ± 0.10 (Tshaj tawm)
daim ntawv hmoov
xim dawb mus rau dawb
InChI InChI=1S/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16({13}}){14} }/h2-10H,1H3,(H2,17,19,20)
InChIKey LNPDTQAFDNKSHK-UHFFFAOYSA-N
SMILES C1(S(N)(=O)=O)=CC=C(C2=C(C)ON{{6} }C2C2=CC=CC=C2)C=C1
CAS DataBase Reference 181695-72-7(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 2919279Q3W
NCI Phau ntawv txhais lus ntawm Cancer Terms valdecoxib
NCI Drug Dictionary Bextra
ATC code M01AH03
[Siv]
Valdecoxib yog ib qho tshuaj uas tsis yog tshuaj steroidal anti-inflammatory (NSAID) uas muaj cov tshuaj tiv thaiv kab mob, tshuaj tua kab mob thiab tshuaj tua kab mob hauv cov qauv tsiaj. Nws yog ib qho muaj zog thiab xaiv inhibitor ntawm prostaglandin synthesis feem ntau los ntawm inhibition ntawm COX-2. Valdecoxib yog siv los txo qee cov tsos mob tshwm sim los ntawm kev mob caj dab (rheumatism), xws li mob, o, txhav, thiab mob pob qij txha.
Cim npe nrov: 4-(5-methyl-3-phenyl-4-isoxazolyl) benzenesulfonamide, Tuam Tshoj, tuam ntxhab, lwm tus muag khoom, Hoobkas, lag luam wholesale, kev cai
