Kev piav qhia
Cov khoom no yog cov tshuaj ncua kev kawm roj ntawm cov khoom zoo. Thaum sawv ntsug, cov khoom zoo nyob; tom qab co, nws dhau los ua ib yam, tawm -dawb mus rau lub teeb xim av ncua kev kawm ntawv.
Pharmacological Action
Pharmacodynamics:Cefquinome yog thib plaub - tiam cephalosporin tshuaj tua kab mob tshwj xeeb rau kev siv kws kho tsiaj. Nws muaj cov kab mob bactericidal los ntawm inhibiting cell phab ntsa synthesis, muaj dav -spectrum antibacterial kev ua si, thiab yog ruaj khov rau -lactamases. Hauv vitro susceptibility tests tau pom tias cefquinome muaj txiaj ntsig zoo rau cov kab mob Gram-positive thiab Gram-negative, xws li Escherichia coli, Citrobacter spp., Klebsiella spp., Pasteurella spp., Proteus spp., Salmonella spp., Serratia marcescens, Serratia marcescens, Bacillus spp., Corynebacterium spp., Staphylococcus aureus, Streptococcus spp., Bacteroides spp., Clostridium spp., Fusobacterium spp., Prevotella spp., Actinobacillus spp., thiab Erysipelotiohria ntawm lwm tus,
Pharmacokinetics:Tom qab kev tswj hwm intramuscular ntawm 2 mg cefquinome ib kg lub cev qhov hnyav hauv npua, qhov siab tshaj plaws plasma concentration (5.93 ug / ml) mus txog 0.4 teev tom qab txhaj tshuaj. Kev tshem tawm ib nrab ntawm lub neej yog kwv yees li 1.4 teev, thiab thaj chaw nyob hauv qab lub sijhawm plasma concentration-time nkhaus (AUC) yog 12.34 ug·h / ml.
Kev ua thiab siv
-lactam tshuaj tua kab mob. Nws yog qhia rau kev kho mob ntawm tus kab mob ua pa nyob rau hauv npua los ntawm Pasteurella multocida los yog Actinobacillus pleuropneumoniae.
Dosage thiab Administration
Intramuscular txhaj tshuaj ib zaug: 0.08-0.12 mL ib kg lub cev qhov hnyav hauv npua, ib zaug ib hnub, rau 3-5 hnub sib law liag.
Kev Phem Tsis Zoo
Tsis muaj kev phiv tshwm sim thaum siv raws li cov tshuaj thiab kev tswj hwm.
Cov kev ceev faj
(1) Contraindicated nyob rau hauv cov tsiaj hypersensitive rau -lactam tshuaj tua kab mob.
(2) Khaws kom deb ntawm cov neeg mob siab rau penicillins thiab cephalosporins.
(3) Co zoo ua ntej siv.
Lub Sijhawm rho nyiaj
Lub sij hawm rho tawm hauv npua: 72 teev.
Specification
Muab xam raws li C₂₃H₂₄N₆O₅S₂:
(1) 5 ml: 0.125 g
(2) 10 ml: 0.25 g
(3) 20 ml: 0.5 g
(4) 30 ml: 0.75 g
(5) 50 ml: 1.25 g
(6) 100 ml: 2.5 g
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