Dab tsi yogPiperazine Citrate ntsiav tshuaj?
Pharmacodynamics:Piperazine siv cov curare -zoo li cuam tshuam rau cov kab mob nematodes. Nws cov txheej txheem ntawm kev ua haujlwm cuam tshuam nrog hyperpolarizing cov paj hlwb ntawm cov hlab ntsha ntawm cov hlab ntsha neuromuscular, thaiv kev sib kis ntawm cov hlab ntsha impulses. Qhov no ua rau tuag tes tuag taw thiab immobilization ntawm cov kab mob cab, ua rau nws tshem tawm ntawm tus tswv tsev thiab tom qab tuag. Tsis tas li ntawd, piperazine tuaj yeem cuam tshuam succinate synthesis hauv cov cab, cuam tshuam nrog nws lub zog metabolism.
Piperazine muaj txiaj ntsig zoo tiv thaiv qee yam nematodes parasitizing nees, npua, dev, miv, thiab nqaij qaib. Nws muaj txiaj ntsig zoo tiv thaiv ascarids hauv txhua hom tsiaj txhu thiab muaj txiaj ntsig zoo tiv thaiv Cyathostomum thiab paub tab Oxyuris equi (pinworms) hauv nees. Ib koob tshuaj piperazine zoo heev (kwv yees li 100%) tawm tsam Oesophagostomum spp. (nodular worms) nyob rau hauv npua. Nws muaj txiaj ntsig zoo rau Toxocara canis thiab Toxascaris leonina. Kev ua tau zoo (tshaj 90%) tiv thaiv kab mob ua ntej yug menyuam Toxocara canis tau ua tiav hauv cov menyuam dev kho thaum muaj hnub nyoog 2, 4, 6, thiab 8 lub lis piam.
Pharmacokinetics:Piperazine yog nkag tau yooj yim los ntawm txoj hnyuv thiab feem ntau metabolized (60% -70%). Unmetabolized niam txiv cov tshuaj tau tawm hauv cov zis hauv 24 teev tom qab tswj hwm. Piperazine tuaj yeem kuaj pom hauv cov zis tsis pub dhau 30 feeb tom qab- kev tswj hwm.
Dab tsi yog Physicochemical Properties ntawmPiperazine Citrate ntsiav tshuaj?
Cov khoom no yog ib ntsiav tshuaj dawb.
Siv
Dab tsi yogPiperazine Citrate ntsiav tshuajsiv rau?
Piperazine anthelmintic tus neeg sawv cev. Feem ntau siv rau ascariasis nyob rau hauv cov tsiaj nyeg thiab nqaij qaib, thiab kuj rau equine oxyuriasis, trichonematosis, thiab Oesophagostomum kab mob nyob rau hauv nyuj, yaj, thiab npua.
Kev noj tshuaj
Ntau npaum li casPiperazine Citrate ntsiav tshuajyuav tsum muab rau ib tug tsiaj?
Kev tswj ntawm qhov ncauj:Ib koob tshuaj: 0.5 ntsiav tshuaj ib kg lub cev hnyav rau nees thiab nyuj; 0.5-0.6 ntsiav tshuaj rau yaj thiab npua; 0.5 ntsiav tshuaj rau nqaij qaib; 0.2 ntsiav tshuaj rau dev.
Cov teebmeem
Dab tsi yog qhov muaj feem cuam tshuam ntawmPiperazine Citrate ntsiav tshuajnyob rau hauv ntau hom tsiaj?
(1) Cov kev phiv tshuaj tsis tshua muaj nyob ntawm qhov pom zoo, tab sis raws plab, ntuav, thiab ataxia tuaj yeem tshwm sim hauv dev.
(2) Hauv cov dev zoo rau microfilariae, kev siv cov khoom no tuaj yeem ua rau muaj kev poob siab hypovolemic-zoo li cov tshuaj tiv thaiv, uas yuav ua rau tuag taus anaphylaxis hauv ob peb teev.
Yuav ua li cas yog cov ntau npaum cov ntaub ntawv ntawmPiperazine Citrate ntsiav tshuaj?
0.5g.
Dab tsi yog Cov Lus Ceeb Toom ntawmPiperazine Citrate ntsiav tshuaj?
(1) Contraindicated nyob rau hauv dev zoo rau microfilariae.
(2) Siv rau cov dev thiab miv tom qab pub mis kom txo tau cov kab mob plab hnyuv.
(3) Lub sijhawm rho nyiaj:nyuj thiab yaj: 28 hnub; npua: 21 hnub; Nqaij qaib: 14 hnub. Lub sij hawm pov tseg qe: 7 hnub.
Cim npe nrov: piperazine citrate ntsiav tshuaj, manufacturers, lwm tus neeg, Hoobkas, lag luam wholesale, customized
